It took a private grower many years to get trees grafted with legally imported branches cleaned off diseases, in quarantine, before those could be planted, legally but in secrecy, on 430 acres in California.

Due to the high susceptibility to “exotic pests and diseases,” this fruit is prohibited from being imported into the US.

But in short: it’s a Japanese hybrid citrus fruit known as Dekopon. If you’re up to reading, here’s an article in the Los Angeles Times from a decade ago that gives a lot of details. I’ve been seeing so-called Sumo Citruses/Mandarins for at least a couple of years, but it wasn’t until my vSO told me its story that I decided to try it (before seeing that ad). So, when I saw the ad in The New Yorker magazine, I registered it as something unusual. The authors have declared no competing interest.How often do you see print ads for a fruit? I’m talking not about store fliers, delivery service leaflets or motivational magazine collages about healthy eating, but actual ads that promote fruits. Our findings also reveal a previously unappreciated role for SUMOylation in promoting centromere clustering. Lem2 has previously been implicated in diverse biological processes, including the promotion of both centromere clustering and silencing, but how these distinct activities are coordinated was unclear our observations suggest a model whereby SUMOylation may serve as a regulatory switch, modulating Lem2 interactions with competing partner proteins to balance its roles in alternative pathways. Moreover, both effects are at least partially dependent on SUMOylation of the inner nuclear membrane protein Lem2. Unexpectedly, we find that while this localised hyper-SUMOylation impairs centromeric silencing, it can also enhance centromere clustering. Here we show that in fission yeast, delocalisation of the SUMO protease Ulp1 from the nuclear envelope results in centromeric defects that can be attributed to hyper-SUMOylation at the nuclear periphery. Regulation by the small modifier SUMO is heavily dependent on spatial control of enzymes that mediate the attachment and removal of SUMO on substrate proteins.

Sumo clementine